Rationale for Medium Cutoff Membranes in COVID-19 Patients Requiring Renal Replacement Therapy

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  • "Pathways through which HDx could play a role in reducing the rate of severe infections
    - reduced inflammation, as supported by lowering of the concentration of inflammatory cytokines and reduced transcription of pro-inflammatory cytokines in peripheral leukocytes
    - reduced serum concentration of free light chains (FLC) since their retention in CKD patients is associated with in vitro inhibition of leukocyte chemotaxis"